Browsing Faculty of Health Sciences by Title

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Acceptance of the coronavirus disease 2019 vaccine among medical students in Uganda.

Kanyike, Andrew Marvin; Olum, Ronald; Kajjimu, Jonathan; Ojilong, Daniel; Akech, Gabriel Madut; Nassozi, Dianah Rhoda; Agira, Drake; Wamala, Nicholas Kisaakye; Asiimwe, Asaph (BMC., 2021)

Background: COVID-19 is still a major global threat for which vaccination remains the ultimate solution. Uganda reported 40,751 cases and 335 deaths as of 9 April 2021 and started its vaccination program among priority ...
Acute and subacute toxicity profile of ethanolic stem bark extract of Albizia coriaria Welw. ex Oliv. in Wistar albino rats

Obakiro, Samuel Baker; Kiyimba, Kenedy; Owor, Richard Oriko; Andima, Moses; Lukwago, Tonny Wotoyitide; Kawuma, Carol; Gavamukulya, Yahaya; Nabatanzi, Alice; Kibuule, Dan; Kato, Charles Drago; Anywar, Godwin; Waako, Paul (Elsevier Inc., 2024)

Albizia coriaria (Fabaceae) crude extracts are key ingredients of several licensed and unlicensed herbal products in East Africa. However, there is limited and often contradicting information regarding its toxicity. We ...
Adjunctive moxibustion treatment for tuberculosis: A randomised clinical trial investigating potential efficacy and comparative safety

Ibanda, Hood Ahmed; Mubiru, Frank; Musiba, Rogers; Itaya, Sachiko; Craig, Jenny; Young, Merlin; Waako, Paul (Elsevier, 2018)

Introduction Small cone direct moxibustion (‘moxa’) is known to have been used in Japan at the height of its tuberculosis (TB) epidemic in the pre-antibiotic era with documented reports of efficacy including one scientific ...
Advances in green nanobiotechnology: Data for synthesis and characterization of silver nanoparticles from ethanolic extracts of fruits and leaves of Annona muricata

Gavamukulya, Yahaya; El-Shemy, Hany A.; Meroka, Amos M.; Madivoli, Edwin S.; Maina, Esther N.; Wamunyokoli, Fred; Magoma, Gabriel (Elsevier, 2019)

In this data article, data obtained from an efficient, eco-friendly and low-cost method for the synthesis and recovery of Silver nanoparticles (AgNPs) using ethanolic extracts of Annona muricata fruits and leaves as ...
Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness

Kiguli, Sarah; Maitland, Kathryn; George, Elizabeth C.; Olupot-Olupot, Peter; Opoka, Robert O.; Engoru, Charles; Akech, Samuel; Nyeko, Richard; Mtove, George; Reyburn, Hugh; Levin, Michael; Babiker, Abdel G.; Gibb, Diana M.; Crawley, Jane (BMC, 2015)

Background: Severe anaemia in children is a leading cause of hospital admission and a major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood transfusion in this vulnerable group. Methods: ...
Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects

Gavamukulya, Yahaya; Wamunyokoli, Fred; El-Shemy, Hany A. (Medknow Publications, 2017)

Annona muricata (A. muricata) is a tropical plant species belonging to family Annonaceae and known for its many medicinal uses. This review focuses on the research history of its traditional uses, phytochemicals, ...
Antimicrobial resistance and rational use of medicine :

Kanyike, Andrew Marvin; Olum, Ronald; Kajjimu, Jonathan; Owembabazi, Shebah; Ojilong, Daniel; Nassozi, Dianah Rhoda; Amongin, Joan Fidelia (Research Square, 2022-02)

Background: Antimicrobial resistance (AMR) is an important global health concern, projected to contribute to signicant mortality, particularly in developing countries. This study aimed to determine the knowledge, perceptions ...
Appropriateness and affordability of prescriptions to diabetic patients attending a tertiary hospital in Eastern Uganda :

Obakiro, Samuel Baker; Kiyimba, Kenedy; Napyo, Agnes; Kanyike, Andrew Marvin; Mayoka, Wilberforce John; Nnassozi, Aishah Ggalabuzi; Aguti, Beatrice; Akech, Gabriel Madut; Waako, John Paul (Busitema University ; Plos One., 2021-01-05)

Irrational prescription of drugs can lead to high cost of treatment thus limiting access to essential medicines. We assessed the affordability and appropriateness of prescriptions written for diabetic patients in Eastern ...
Assessment of myocardial function and injury by echocardiography and cardiac biomarkers in African children with severe plasmodium falciparum malaria

Kotlyar, Simon; Olupot-Olupot, Peter; Nteziyaremye, Julius; Akech, Samuel; Uyoga, Sophie; Muhindo, Rita; Moore, Christopher L.; Maitland, Kathryn (Lippincott, Williams & Wilkins, 2017)

Objectives: Perturbed hemodynamic function complicates severe malaria. The Fluid Expansion as Supportive Therapy trial demonstrated that fluid resuscitation, involving children with severe malaria, was associated with ...
Awareness of antimicrobial resistance among primary health care workers in Buyende District, rural Eastern Uganda

Ahebwa, Amelia; Akol, Walter; Achong, Emmanuel; Mugerwa, Timothy; Nakayenga, Aminah; Nekaka, Rebecca (SCIENCEDOMAIN International, 2017)

Aim: The aim of this study was to assess the awareness of antimicrobial resistance among Primary Health Care Workers in Buyende district. Methods: This was a cross-sectional study employing qualitative and quantitative ...
Bacterial aetiology and antibiotic susceptibility profile of post operative sepsis among surgical patients in a tertiary hospital in rural Eastern Uganda

Masifa, George; Iramiot, Jacob Stanley; Muhindo, Rita; Olupot-Olupot, Peter; Nanteza, Ann (Science Domain International, 2018)

Background: Post-operative wound sepsis remains a surgical challenge of public health concern constituting approximately 20% of the health care-associated nosocomial infections. This study aimed at determining the prevalence ...
Bacterial and fungal contaminants in mycobacterium tuberculosis cultures at national tuberculosis referral laboratory-Kampala

Tushabe, John Vianney; Katuura, Esther; Iramiot, Jacob Stanley (Science Domain International, 2017)

Aim: This study was aimed at identification of fungal and bacterial contaminants in Tuberculosis cultures at the Uganda National Reference Laboratory (NTRL). Methods: The cultures were previously grown on Lowenstein-Jensen ...
Basic life support, a necessary inclusion in the medical curriculum :

Ssewante, Nelson; Wekha, Godfrey; Iradukunda, Angelique; Musoke, Phillip; Kanyike, Andrew Marvin; Nabukeera, Germinah; Wamala, Nicholas Kisaakye; Zziwa, Wilson; Kamuhangire, Lauben; Luggya, Tonny Stone; Tagg, Andrew; Kajjimu, Jonathan (BMC Medical Education, 2022)

Background: Uganda continues to depend on a health system without a well-deined emergency response system. This is in the face of the rising cases of out-of-hospital cardiac arrest contributed largely to the high incidence ...
Bottlenecks and opportunities towards achieving the targeted 95-95-95 HIV services in a rural district in Eastern Uganda [version 1; peer review: awaiting peer review]

Namenkere, Monkya Samuel; Ayaa, Mary Stella; Sukuku, Linda; Kharono, Juliet; Mugabi, Charles; Chelangat, Benina; Olwedo, Mary Abwola; Nabasumba, Carol; Oboth, Paul; Osele, Julius; Nekaka, Rebecca; Iramiot, Jacob Stanley (f1000research, 2022-12)

Background: Uganda has made progress in reducing its HIV prevalence from 7.3% in 2011 to 6% in 2017, however, more needs to be done to meet the World Health Organization (WHO) target of 95% of the population knowing their ...
Cervicovaginal bacteriology and antibiotic sensitivity patterns among women with premature rupture of membranes in Mulago Hospital, Kampala, Uganda: A cross-sectional study

Musaba, Milton W.; Kagawa, Mike N.; Kiggundu, Charles; Kiondo, Paul; Wandabwa, Julius (Hindawi Publishing Corporation, 2017)

Background. A 2013 Cochrane review concluded that the choice of antibiotics for prophylaxis in PROM is not clear. In Uganda, a combination of oral erythromycin and amoxicillin is the 1st line for prophylaxis against ...
Children’s Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia

Maitland, Kathryn; Kiguli, Sarah; Opoka, Robert O.; Olupot-Olupot, Peter; Engoru, Charles; Njuguna, Patricia; Bandika, Victor; Mpoya, Ayub; Bush, Andrew; Williams, Thomas N.; Grieve, Richard; Sadique, Zia; Fraser, John; Harrison, David; Rowan, Kathy (Wellcome Trust, 2018)

Background: In Africa, the clinical syndrome of pneumonia remains the leading cause of morbidity and mortality in children in the post-neonatal period. This represents a significant burden on in-patient services. The ...
Clinical and immunological outcomes of a national paediatric cohort receiving combination antiretroviral therapy in Uganda

Kiboneka, Andrew; Wangisi, Jonathan; Nabiryo, Christine; Tembe, Juliet; Kusemererwa, Sylvia; Joffres, Michel; Olupot-Olupot, Peter; Anema, Aranka; Cooper, Curtis L.; Montaner, Julio S.; Mills, Edward J. (Lippincott, Williams & Wilkins, 2008)

Objective: We aimed to evaluate clinical and immunological outcomes of paediatric patients receiving combination antiretroviral therapy (cART) enrolled in The AIDS Support Organization (TASO) Uganda national HIV/AIDS ...
Co-trimoxazole or multivitamin multimineral supplement for post-discharge outcomes after severe anaemia in African children: a randomised controlled trial

Maitland, Kathryn; Olupot-Olupot, Peter; Kiguli, Sarah; Chagaluka, George; Alaroker, Florence; Opoka, Robert O; Mpoya, Ayub; Walsh, Kevin; Engoru, Charles; Nteziyaremye, Julius; Mallewa, Machpherson; Kennedy, Neil; Nakuya, Margaret; Namayanja, Cate; Kayaga, Julianne; Nabawanuka, Eva; Sennyondo, Tonny; Aromut, Denis; Kumwenda, Felistas; Bates, Imelda; von Hensbroek, Michael Boele; Evans, Jennifer A; Uyoga, Sophie; Williams, Thomas N; Frost, Gary; George, Elizabeth C.; Gibb, Diana M.; Walker, A Sarah (Elsevier, 2019)

Background Severe anaemia is a leading cause of paediatric admission to hospital in Africa; post-discharge outcomes remain poor, with high 6-month mortality (8%) and re-admission (17%). We aimed to investigate ...
Comparison of arterial stiffness in preeclamptic and normotensive pregnant women from a semirural region of South Africa

Namugowa, A.; Iputo, J.; Wandabwa, Julius; Meeme, A.; Buga, G. A. B. (Taylor & Francis, 2017)

Background: Preeclampsia is associated with arterial stiffness and endothelial dysfunction. The pathophysiology of arterial tone in preeclampsia has not been well described in rural African population, where the incidence ...
Coronavirus disease 2019 on routine testing in eclampsia :

Kalsar, Pradip; Datta, Shreya; Kalsar, Arbabasu; Kanyike, Andrew Marvin (BMC., 2022)

Background: Coronavirus disease 2019 has been associated with adverse pregnancy outcomes, including preeclampsia. Coronavirus disease 2019 and preeclampsia have overlapping clinical features and are therefore Challenging ...

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